Since there is NO SINGLE diagnostic method that can detect Tuberculosis Infection, why not add another TB test to your current tests menu?   New  SERUM test  for Tuberculosis

As medical technologists, we all know there is NO single diagnostic method that can detect all TB cases! Clinicians typically rely on a battery of methods such as:

	Advantages	Disadvantages
Chest X-ray	· Non-invasive     · Test result available immediately	· Cannot differentiate Active or Non-Active    TB     · Useless in detecting extrapulmonary TB     · Exposure to radiation.
Smear test      Sputum/body fluid	· Non-invasive    · Test result available within hours	· Detection rate is less than 30%    · Non-detectable if less than 5,000         organisms/ml in sputum.    · Multiple samples required
Culture      Sputum/body fluid	· Reference method    · Detection rate is 80% plus for confirmed     pulmonary TB (normally with repeating      samples of 3)	· reporting time takes 6 to 8 weeks!    · Multiple samples required   · Detection rate is 40% in screening (where      only one sample is used)
PCR	· Reporting time faster than conventional method  · Very specific	· Labor intensive     · Reporting time takes days!  · Expensive   · Current markers for TB not highly specific    for active TB, thus not highly sensitive.
Rapid test     Serum/Whole Blood	· Fast reporting time, 15 min.    · detects active TB only    · detects both pulmonary and extrapulmonary TB    · detection rate, 80% plus   · Serum, whole blood, CSF, pleural fluid  · Ideal for screening

 

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